Posts

COMBER pilot and lab units for reproducible process results and reliable scale-up

Pilot plants and laboratory equipment are essential for optimal and reliable process results. Various tests and simulations clarify all important questions in advance, thus ensuring reliable scale-ups and your success when investing in the ideal production machine. In order to develop new products or optimise existing ones, the COMBER pilot and lab units provide reproducible […]

Live Webinar from COMBER Workshop: Twin Pressofiltro® PF 50

Interested in learning more about the features of the two identical Filter Dryers PF 50? With this machines, ready for shipment, we show you some customized solutions and newly developed features of these pilot units. Take the opportunity to learn more about the machine details presented on-site, about an interesting application in the chemical industry […]

COMBER received ISO 45001 certification: big milestone for occupational health and safety

COMBER has taken a big step and completed its certification according to ISO 45001:2018. Apart from the ISO 9001, COMBER now has also proven the health and safety aspects regarding the internal organisation. This certification means that COMBER is complying with the requirements for an occupational health and safety management system for proactive improvements and […]

COMBER: celebrating 60 years!

For 60 years, COMBER has been a leading supplier of Nutsche filters, pressure filter dryers and batch type vacuum dryers for pharmaceutical and chemical production. It is indeed from 1960 that COMBER, now part of part of HEINKEL Drying and Separation Group (HDSG), offers its customers high quality machinery, all Made in Italy.

COMBER Pressofiltro® Filter Dryer for aseptic API and fine chemicals

For the manufacture of sterile parenterals, i.e. substances which are intended for injection, infusion or implantation into the human or animal body, the issue of sterilization of process equipment is of high priority. In addition to a local cleaning of a process plant, also known as Clean in Place (CIP), many pharmaceutical processes require therefore a subsequent sterilization (sterilization in place). For example this can be ensured by steam sterilization. In this respect all product contacted surfaces should be coated safely and for a defined period with pressurized steam of at least 121 °C.

Remote maintenance included

HEINKEL has optimised system and machine control. The corresponding HMI panels work with the S7 TIA control system from Siemens and thus facilitate the operation of centrifuges, (filter) dryers and mixers of both the corporate HEINKEL, BOLZ-SUMMIX and COMBER brands and third-party makes.

Avoiding contamination by “lift-off” mechanical seal

In the field of mechanical and thermal separation, the HEINKEL Group often uses mechanical seals besides shaft seals and stuffing boxes. For the manufacturing of API (Active pharmaceutical ingredients) and fine chemicals, usually non contacting, gas lubricated (lift-off) mechanical seals are used. In the field of horizontal dryers, this solution which prevents cross contamination is increasingly applied by COMBER customers who prefer inert gases as a lubricant.