Nutsche Filters & Filter Dryers with containment system

Pressofiltro® Series PF 5 - PF 6000 with Containment systems

COMBER Pressofiltro® agitated Nutsche filters or filter dryers with containment systems provide protection of the operators against hazardous materials and equally provide product or process safety against possible contamination from external particles. 

COMBER Pressofiltro® agitated Nutsche filter dryers equipped with isolators are increasingly being used for biotechnological and pharmaceutical filtration and drying tasks in contained environments. 

Isolators provide optimum operator and product protection in production lines for API‘s, intermediates and fine chemicals for products classified up to category OEL 5 level, i.e. extremely toxic and/or with extremely high pharmacological activity.

 

 

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Inerting

Prior to feeding slurry into the agitated Nutsche filter or filter dryer the vessel interior is inerted by a controlled displacement of the oxygen containing atmosphere with Nitrogen. This procedure prevents the potential formation of an explosive atmosphere in the vessel interior.

The washing liquid is evenly distributed over the entire filter cake surface using a wash ring with spray nozzles. By again pressurizing the vessel interior the washing liquid is forced thru the filter cake, displacing any remaining mother liquor and is discharged the same way as the mother liquor during the filtration.


In the reslurry washing process the washing liquid is added to the vessel and mixed with the filter cake using the agitator. By again pressurizing the vessel interior the washing liquid is forced thru the filter cake, displacing any remaining mother liquor and is discharged the same way as the mother liquor during the filtration.

Technical data

Special properties for the customer’s benefit:

  • Additional sensors and control system to find out when the sterilization process finishes
  • Validatable steam sterilization
  • calculation, design and manufacture in compliance with Pressure Equipment Directive 97/23/EG or/and ASME pressure vessel code, section VIII, with U-stamp as well as with cGMP and FDA guidelines
  • EG type examination certificate 03ATEX0246X per the 94/9/EC directive, or with electrical components UL approved for operation in a Class 1, Division 1 or 2, Groups C&D environment
  • double mechanical seal, externally interchangeable, non contacting gas-lubricated (lift-off), dry running contact (contacting sliding surfaces) or liquid-lubricated seal
  • sampler valve
  • hydraulic pre-piping made of stainless steal, pre-wiring on terminal box made of stainless steal
  • integral CIP-/ SIP System


Options:

  • additional heating with microwaves to reduce the drying process
  • pressure-resistant and sterile versions, isolators (glove box), DQ, IQ, OQ qualification
  • autonomic PLC control or connected to PMSX, heavy current box

Technical data

Dryer
type
 
Internal
Ø
mm
Filter area

 
Nominal volume
l
 
Cake volume max.
max.
l
Speed
max.
1/min
Drive
kw
PF 50 400 0.10 50 18 55 2.2
PF 100 500 0.20 100 32 50 4.0
PF 200 640 0.32 230 80 74 4.0
PF 250 700 0.38 280 115 70 5.5
PF 350 800 0.50 400 150 60 5.5
PF 500 S 875 0.60 500 180 52 7.5
PF 500 955 0.70 640 210 46 7.5
PF 750 1050 0.85 770 340 40 7.5
PF 1000 S 1150 1.00 930 415 40 11.0
PF 1000 1270 1.26 1140 505 37 11.0
PF 1500 1380 1.50 1500 750 30 15.0
PF 2000 1600 2.00 2000 1000 30 18.5
PF 2500 1800 2.50 2500 1250 25 18.5
PF 3000 1960 3.00 3000 1500 25 22
PF 4000 2260 4.00 4000 2000 21 22
PF 5000 2535 5.00 5000 2500 18 30
PF 6000 2765 6.00 6000 3000 17 30